If you are suffering from a serious problem like impotence then these are the best tablets to solve. Vigora 100 drug is taken 1 hour before intercourse, after which its effect lasts for 4-5 hours, after which you can enjoy sex better. Best for ED Treatments. You can feel sex better after taking Vigora 100mg drug, Vigora 100 Mg can be a side effect if not once a day.